Final answer:
Russell Bodies are large accumulations of immunoglobulins within the cytoplasm of Plasma Cells. They are seen in conditions such as multiple myeloma and indicate abnormal immunoglobulin production.
Step-by-step explanation:
Russell Bodies are structures that may be seen within the cytoplasm of Plasma Cells. They are named after Alexander Russell, who first described them in 1890. Russell Bodies are large accumulations of immunoglobulins (antibodies) that have been produced by the plasma cells but cannot be properly secreted.
When viewed under an electron microscope, Russell Bodies appear as dense, amorphous masses within the cytoplasm. They are often seen in conditions such as multiple myeloma, a type of cancer that originates in plasma cells. The presence of Russell Bodies is an indication of abnormal immunoglobulin production.