Final answer:
During B cell maturation, stromal cells in the bone marrow provide support and create a microenvironment for B cell development. They produce cytokines that stimulate the differentiation and maturation of B cells. Stromal cells also play a role in regulating B cell selection and promoting B cell tolerance.
Step-by-step explanation:
B cells interact with stromal cells during development through a process called B cell maturation. B cell maturation occurs in the bone marrow, where stromal cells provide support and create a microenvironment for B cell development. Stromal cells produce cytokines that stimulate the differentiation and maturation of B cells.
Additionally, stromal cells help regulate the selection and survival of B cells by presenting self-antigens and promoting B cell tolerance.