Question

You inject (intravenously) a 70 Kg patient with 30 mg of drug

that has a Vd of 5 L/Kg and an elimination half life of 3 hr.
What is the elimination rate constant (K) for this
drug?

Answer 1

The elimination rate constant (K) for the drug can be calculated using the formula: K = ln(2) / t1/2, where t1/2 is the elimination half-life. Substituting the given half-life of 3 hours, the calculation yields K ≈ 0.231.

Step-by-step explanation:

The elimination rate constant (K) for a drug can be calculated using the formula:

K = ln(2) / t1/2

Where t1/2 is the elimination half-life of the drug.

In this case, the elimination half-life is given as 3 hours, so we can substitute it into the formula:

K = ln(2) / 3

To calculate this, we can use a calculator:

K ≈ 0.231