Question

Determine if the following would be compatible or incompatible in the major crossmatch.

Recipient: O pos Donor: A pos
Recipient AB pos Donor: B pos
Recipient: A neg Donor: O pos
Recipient: B neg Donor: AB neg

Answer 1

The major crossmatch determines the compatibility of donor and recipient blood types. The given combinations are analyzed to determine if they are compatible or incompatible based on the presence of antibodies and antigens.

Step-by-step explanation:

The major crossmatch involves testing for compatibility between the donor's antigens and the recipient's antibodies. In the case of the given blood groups:

1. Recipient: O pos Donor: A pos - This combination is incompatible because the recipient has antibodies against the A antigen, which will cause agglutination of the donor's A-positive red blood cells.
2. Recipient: AB pos Donor: B pos - This combination is compatible because the recipient does not have antibodies against the B antigen, and there are no antibodies in the donor plasma that will react with the recipient's red blood cells.
3. Recipient: A neg Donor: O pos - This combination is compatible because the recipient does not have antibodies against the A antigen, and there are no antibodies in the donor plasma that will react with the recipient's red blood cells.
4. Recipient: B neg Donor: AB neg - This combination is compatible because the recipient does not have antibodies against the B antigen, and there are no antibodies in the donor plasma that will react with the recipient's red blood cells.