Final answer:
The clearance rate for a drug with a volume of distribution of 5 L/Kg and an elimination half-life of 3 hours for a 70 Kg patient is approximately 80.85 L/hr.
Step-by-step explanation:
You are asking how to calculate the clearance rate for a drug given to a patient with a volume of distribution (Vd) of 5 L/Kg and an elimination half-life of 3 hours. To calculate clearance (Cl), we can use the following equation:
Cl = (0.693 * Vd) / t1/2
Where 0.693 is the natural logarithm of 2 (used for half-life calculations), Vd is the volume of distribution, and t1/2 is the elimination half-life. Plugging in the values:
Cl = (0.693 * 5 L/Kg * 70 Kg) / 3 hr
Cl = 80.85 L/hr
Therefore, the clearance rate for this drug would be approximately 80.85 L/hr.