Question

4. Doctor ordered fligrastim (Neupogen) 15 mcg/kg/day in two equal doses subcutaneously for a

patient who weighs 200 lb. Medication available is Neupogen solution labeled 300 mcg/mL.
How many mL will the nurse administer per dose? Round your answer to the nearest tenth.

Answer 1

To find the volume of Neupogen to administer per dose, convert the patient's weight to kilograms, calculate the daily dose, divide it by two for two equal doses, and then divide by the medication concentration.

The nurse will administer 2.3 mL per dose.

Step-by-step explanation:

The question asks us to calculate the volume of Neupogen solution a nurse should administer per dose if the prescribed dose is 15 mcg/kg/day, given in two equal doses subcutaneously, for a patient weighing 200 lb.

The medication available is Neupogen solution labeled 300 mcg/mL.

First, we convert the patient's weight from pounds to kilograms, knowing that 1 kg = 2.20462 lb:

• 200 lb * (1 kg / 2.20462 lb) = 90.7185 kg (approx)

Next, we calculate the total daily dose in micrograms:

• 90.7185 kg * 15 mcg/kg = 1360.7775 mcg/day

Since the daily dose is divided into two equal doses, we find one dose:

• 1360.7775 mcg/day / 2 = 680.38875 mcg/dose

To find the volume to administer per dose, we divide by the concentration of the solution:

• 680.38875 mcg/dose / (300 mcg/mL) = 2.2680 mL/dose

Finally, we round the volume to the nearest tenth:

• 2.3 mL/dose

So the nurse will administer 2.3 mL per dose.