Final answer:
In Griffith's transformation experiments, the relationship between a rough colony and a smooth colony can be compared to pneumoni and mouse. The injection of heat-killed S strain and live R strain resulted in the death of the mouse and the recovery of S strain from the dead mouse. This showed that the heat-killed S strain transformed the R strain into the pathogenic S strain.
Step-by-step explanation:
The relationship between a rough colony and a smooth colony can be compared to pneumonia and mouse. In Griffith's transformation experiments, he used two strains of S. pneumoniae: the smooth (S) strain, which is pathogenic and causes death, and the rough (R) strain, which is non-pathogenic. When a mouse was injected with the heat-killed S strain and the live R strain, the mouse died and S strain was recovered from the dead mouse. This demonstrated that something had passed from the heat-killed S strain to the R strain, transforming the R strain into an S strain.