Question

HMG-CoA inhibitors is known to cause elevations in which

of the following laboratory examinations?

a. SGPT
b. SGOT
c. Alkaline Phosphates
d. Bilirubin

Answer 1

HMG-CoA inhibitors, also known as statins, can cause elevations in liver enzymes, specifically SGPT and SGOT.

Step-by-step explanation:

HMG-CoA inhibitors, also known as statins, are a group of drugs used to lower cholesterol levels in the blood. While they are generally well-tolerated, they can cause certain laboratory abnormalities. One of these abnormalities is elevations in liver enzymes, specifically SGPT (a) and SGOT (b). These enzymes are typically measured to assess liver function, and elevated levels may indicate liver damage caused by the HMG-CoA inhibitors.

It is important for patients taking HMG-CoA inhibitors to have regular monitoring of liver function tests to detect any elevations in these enzymes. If abnormal results are detected, the medication may need to be adjusted or discontinued to prevent further liver damage.