Final answer:
Yes, the abuse of amphetamine is linked to neurotransmitter activity, specifically through blocking dopamine reuptake and stimulating its release, leading to potential abuse and addiction.
Step-by-step explanation:
The statement that abuse of amphetamine has been linked to the neurotransmitter is true. Amphetamine, which is a potent central nervous system stimulant, is known to block the reuptake of dopamine and stimulate its release. This mechanism of action is similar to that of cocaine. While amphetamines are legally prescribed for conditions such as ADHD and narcolepsy, due to their effects on neurotransmitter activity within the brain, especially in areas associated with impulse control like the prefrontal cortex and basal ganglia, they have a high potential for abuse and addiction. The recreational use of amphetamines can lead to a range of harmful consequences including neurotoxicity, which differs from effects seen with prescribed therapeutic use.