Final answer:
B cells are not part of the second line of defense in the immune system.
Step-by-step explanation:
The cell type that is NOT part of the second line of defense is B cells. The second line of defense in the immune system includes cells such as eosinophils, mast cells, and basophils, all of which play a role in the inflammatory response. Eosinophils are involved in killing parasites, mast cells release chemicals that trigger inflammation, and basophils release chemicals involved in the allergic response. However, B cells are not part of the second line of defense, but rather part of the adaptive immune response, which is the third line of defense.