Final answer:
Cholecystokinin (CCK) and secretin are the two main inhibitors of gastric motility, as they regulate the secretion of pancreatic juices and bile, and slow down gastric emptying to aid digestion in the small intestine.
Step-by-step explanation:
The two major inhibitors of gastric motility mentioned on page 880 are likely Cholecystokinin (CCK) and secretin. These hormones are part of the hormonal control of the digestive system. CCK is secreted by the duodenum in response to the presence of proteins and fats, and it stimulates the secretion of pancreatic enzymes and bile, as well as enhances the activity of secretin. Secretin is released in response to the acidity of chyme in the duodenum and prompts the duct cells to release bicarbonate-rich pancreatic juice. These actions collectively inhibit gastric motility by slowing down the gastric emptying and reducing the motility of the stomach, facilitating the digestion of nutrients in the small intestine.