Final answer:
The primary mechanism of ATP synthesis in oxidative phosphorylation is ATP synthase enzyme catalysis.
Step-by-step explanation:
The primary mechanism of ATP synthesis in oxidative phosphorylation is ATP synthase enzyme catalysis. ATP synthase is an enzyme complex located in the inner mitochondrial membrane. It uses the energy from the flow of protons across the membrane during electron transport to catalyze the addition of phosphate groups to ADP molecules, producing ATP.