Final answer:
The two major accessory glands associated with the duodenum are the liver and the pancreas. The liver produces bile and the pancreas secretes digestive enzymes.
Step-by-step explanation:
The two major accessory glands associated with the duodenum are the liver and the pancreas.
The liver produces bile, which is stored in the gallbladder and released into the duodenum to aid in the digestion of fats.
The pancreas secretes digestive enzymes that are delivered to the duodenum via the pancreatic duct, helping break down carbohydrates, proteins, and fats.