Final answer:
A sharps container should be closed and prepared for disposal when it is three-quarters full to prevent overfilling and related safety concerns. It must be sterilized by autoclave before disposal and handled according to safety protocols.
Step-by-step explanation:
The proper point at which a sharps container should be closed, sealed, and prepared for disposal is when it is approximately three-quarters full. This precaution is to avoid overfilling, which can lead to needle sticks and other safety hazards. Once the sharps container reaches this fill level, it should be promptly closed with the built-in locking mechanism, ensuring it's sealed and labeled, if required, according to local regulations, and then disposed of properly. All biohazard waste, including sharps disposal containers, must be sterilized by autoclave before it can be included in the waste stream to ensure the mitigation of potential hazards.
Working with sharps and biohazard materials requires strict adherence to safety protocols. This includes wearing protective gear like coats, face protection, and cut-resistant gloves, and knowing the designated procedures for accidental exposure, waste disposal, and spill management. Following these guidelines helps to maintain a safe environment for everyone in the laboratory.