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The drug binds to the receptors and activates a biological response (opens the ion channel)

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Final answer:

An ion channel-linked receptor, known as an ionotropic receptor, binds to a ligand and opens an ion channel through the membrane, allowing specific ions to pass through and activating a biological response.

Step-by-step explanation:

An ion channel-linked receptor, also known as an ionotropic receptor, binds to a ligand (such as a neurotransmitter) and opens an ion channel through the membrane. When the ligand binds to the receptor, ions can pass through the channel, changing the membrane's charge. This process activates a biological response by allowing specific ions to cross the membrane and affecting the cell's function.

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