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Which intervention may prevent GI bacterial and endotoxin translocation in a critically ill patient with SIRS?

a. Early enteral feedings
b. Surgical removal of necrotic tissue
c. Aggressive multiple antibiotic therapy
d. Strict aseptic technique in all procedures

1 Answer

5 votes

Final answer:

Early enteral feedings (option a) can help maintain gut integrity and potentially prevent bacterial translocation in patients with SIRS, while surgical removal of necrotic tissues and strict aseptic techniques are also important measures. Hence, option a is the most suitable answer.

Step-by-step explanation:

Among the interventions that may prevent gastrointestinal (GI) bacterial and endotoxin translocation in a critically ill patient with Systemic Inflammatory Response Syndrome (SIRS), early enteral feedings are effective. Enteral nutrition supports gut integrity and immune function, and is less likely to contribute to translocation than parenteral nutrition. Surgical removal of necrotic tissue is essential in cases such as gas gangrene where the infection is deep-seated, to reduce bacterial load and source of endotoxins. Strict aseptic technique during medical procedures helps in preventing infections that could exacerbate the patient's condition. However, aggressive multiple antibiotic therapy can disrupt normal gut flora, potentially facilitating overgrowth of resistant organisms like Clostridium difficile, and may not always be the best approach for preventing translocation.

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