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Considered appropriate for ischemic stroke if the total score is more than 4-6 and there is sustained, nonimproving deficit.

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Final answer:

This question addresses the conditions under which clot-busting drugs are appropriate for ischemic stroke treatment, emphasizing the importance of rapid and timely medical intervention to improve outcomes.

Step-by-step explanation:

The question pertains to the treatment of ischemic stroke and factors indicating when it is appropriate to administer certain therapies, such as clot-busting drugs. For an ischemic stroke, rapid treatment significantly increases the chances of a full recovery. The use of recombinant tissue plasminogen activator (rtPA) is crucial and can be most effective if given within a narrow time window after the stroke onset. The severity and progression of a stroke are frequently assessed using a scoring system, and a higher score generally indicates a more severe stroke, often leading to the consideration of aggressive treatments like rtPA. Transient ischemic attacks (TIA) are shorter in duration and the symptoms are typically resolved within 24 hours, often without permanent damage due to the restoration of adequate blood flow.

Understanding the ischemic penumbra is essential in stroke treatment. It's the area of the brain that, although impaired, might be salvageable with prompt medical intervention. This contrasts with the ischemic core, where the tissue damage is often irreversible. Identifying the penumbra helps in determining the potential for recovery and appropriate treatment measures. Recognition of stroke symptoms by bystanders, using the FAST mnemonic, is critical to expedite treatment for the best possible outcomes.

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