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Miosis due to Ach.\\Atropine (-).

1 Answer

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Final answer:

The question addresses the effect of acetylcholine on miosis and how atropine can inhibit this process as a muscarinic antagonist. Atropine's use is limited due to its toxic nature, while pilocarpine is a treatment used to reverse the effects of mydriasis and atropine or scopolamine poisoning.

Step-by-step explanation:

The student's question pertains to the effects of acetylcholine (Ach) on miosis and the antagonistic effects of atropine. In the context of parasympathetic nervous system activity, acetylcholine is released by postsynaptic parasympathetic neurons, leading to the constriction of the pupil, known as miosis. Atropine, on the other hand, is an anticholinergic drug that acts as a muscarinic antagonist at the muscarinic acetylcholine receptors, effectively blocking the effects of acetylcholine and preventing miosis, leading to an opposite condition called mydriasis (dilation of the pupil). Pilocarpine serves as an antidote to atropine or scopolamine poisoning by acting as a muscarinic agonist, reversing mydriasis and reducing intraocular pressure related to glaucoma.

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