Final answer:
Jews were often segregated in parts of cities known as ghettos, which were enclosed and guarded areas with poor living conditions.
Step-by-step explanation:
Jews were often persecuted by Catholics and Protestants throughout history, and many were segregated to parts of cities known as ghettos. In Venice in 1516, the first official ghetto was established to segregate Jews from the rest of the population.
These segregated areas were typically enclosed and guarded, with conditions that were often cramped and unsanitary. Over time, Jews faced various challenges and discrimination, with fluctuations in how they were treated based on the societal and political climate of the era.