Final answer:
Blue discoloration of hepatocytes with Prussian blue staining is indicative of hemosiderosis, a condition characterized by excessive iron storage in the liver cells.
Step-by-step explanation:
Blue discoloration of hepatocytes with Prussian blue staining indicates the accumulation of iron within the liver cells, a condition known as hemosiderosis. This typically occurs due to excessive iron storage and can be seen in various conditions, including chronic hemolytic anemia or in patients who receive multiple blood transfusions. In liver pathology, hemosiderosis may be seen in conjunction with diseases such as alcoholic liver disease. The Prussian blue stain specifically detects iron deposits in tissues, turning them blue upon binding.