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Neurologic symptoms of vitamin E deficiency closely mimic what inherited disease? - Vitamin E is lipid soluble with antioxidant properties

User Marcp
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Vitamin E deficiency can cause neurological symptoms similar to those of adrenoleukodystrophy (ALD), an inherited disease. As an antioxidant, vitamin E preserves cell membranes, including those of nerve cells, preventing cerebral disorders and maintaining myelin integrity. A lack of vitamin E can result in muscular and neurological symptoms, emphasizing its essential role in nervous system health.

Step-by-step explanation:

The neurologic symptoms of vitamin E deficiency closely mimic the inherited disease adrenoleukodystrophy (ALD). Vitamin E, chemically known as alpha-tocopherol, is a lipid-soluble nutrient with potent antioxidant properties. Its deficiency can lead to problems in various body systems due to its role in protecting cell membranes from oxidative damage. While it's essential for many cellular functions, in the nervous system, adequate levels of vitamin E are crucial for preventing cerebral disorders and maintaining myelin integrity - the protective covering of nerve fibers. When vitamin E is deficient, it can lead to symptoms similar to ALD, where lipids accumulate within brain cells, causing damage to the myelin sheath and resulting in neurologic issues.

Vitamin E plays a physiological role in several processes, including the prevention of oxidation of vitamins like vitamin A and the protection of enzymes within muscles, nerves, and gonads. It also has a role in heme synthesis and is necessary for reproductive health. A deficiency in vitamin E can manifest in symptoms ranging from muscular weakness to neurological impairments similar to those seen in ALD, which may include problems with coordination, motor skills, and vision. These consequences highlight the importance of vitamin E in maintaining overall nervous system health.

User Rupak Nepali
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