Final answer:
A combination of nephrotic syndrome and an underlying malignancy suggests a potential paraneoplastic syndrome called paraneoplastic glomerulonephritis.
Step-by-step explanation:
A combination of nephrotic syndrome and an underlying malignancy, such as a solid lung or colon tumor, suggests a potential paraneoplastic syndrome called paraneoplastic glomerulonephritis. Paraneoplastic glomerulonephritis is a rare condition where the tumor releases substances that affect the kidneys and cause proteinuria and other symptoms associated with nephrotic syndrome.
Paraneoplastic glomerulonephritis can occur in various types of cancers, including melanoma, non-small cell lung cancer, Hodgkin lymphoma, and bladder cancer, among others.
Further diagnostic tests, including imaging and biopsy, would be necessary to confirm the presence of a tumor and the exact cause of the nephrotic syndrome.