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3 most important predisposing factors for hypoglycemia in patients with type 1 diabetes? -- what medication should be avoided in patients with DM, as it may exacerbate hypoglycemia and mask its adrenergic symptoms mediated by NE/E?

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Final answer:

The three most important predisposing factors for hypoglycemia in patients with type 1 diabetes are deficiency of insulin, excess of insulin antagonists, and defective or absence of insulin receptors. Insulin should be avoided in patients with diabetes mellitus as it may exacerbate hypoglycemia and mask its adrenergic symptoms mediated by NE/E.

Step-by-step explanation:

The three most important predisposing factors for hypoglycemia in patients with type 1 diabetes are:

Deficiency of insulin (Insulin Dependent Diabetes Mellitus-IDDM-i.e. type-I diabetes).

Defective or absence of insulin receptors on the cells (Insulin Independent Diabetes Mellitus-IIDM-i.e. type-II diabetes).

The medication that should be avoided in patients with diabetes mellitus (DM) as it may exacerbate hypoglycemia and mask its adrenergic symptoms mediated by NE/E is insulin.

Insulin therapy can cause hypoglycemia, and if the insulin dose is too high, it can lead to severe and prolonged hypoglycemia.

This can be dangerous as it can mask the typical symptoms of hypoglycemia, such as sweating, trembling, and increased heart rate, due to the effects of insulin on the sympathetic nervous system.

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