Final answer:
Hemorrhagic cystitis caused by cyclophosphamide chemotherapy can be prevented by aggressive hydration and the administration of mesna, a chemoprotective agent.
Step-by-step explanation:
Hemorrhagic cystitis is a potential side effect of cyclophosphamide chemotherapy. It is characterized by urinary secretion of toxic metabolites, leading to inflammation and bleeding in the bladder. However, this can be prevented by aggressive hydration and administration of a medicine called mesna.
Mesna is a chemoprotective agent that works by detoxifying the harmful metabolites of cyclophosphamide in the urinary system. It helps to prevent the development of hemorrhagic cystitis and other bladder complications.
By keeping the patient well-hydrated and using mesna alongside cyclophosphamide chemotherapy, the risk of hemorrhagic cystitis can be significantly reduced.