Final answer:
Genetically predisposed individuals who are slow metabolizers are at greater risk for developing drug-induced lupus erythematosus (anti-histone antibodies) due to higher drug concentrations in their body.
Step-by-step explanation:
In this context, the subject of the question is Biology. The question is discussing the genetic predisposition of individuals who are slow metabolizers. Slow metabolizers, specifically those who have a slow metabolism for certain drugs, are at a greater risk for developing drug-induced lupus erythematosus (anti-histone antibodies).
For example, individuals who possess certain gene variants responsible for metabolizing drugs slowly may have a higher concentration of the drug in their body. This can lead to an increased risk of developing drug-induced lupus erythematosus, a condition characterized by the production of anti-histone antibodies.
This topic falls under the broader subject of Immunology within Biology.