Final answer:
The first-line treatment for depression that does not cause sexual dysfunction or weight gain is bupropion (Wellbutrin), mirtazapine (Remeron), amoxapine (Asendin), and maprotiline (Ludiomil).
Step-by-step explanation:
The first-line treatment for depression that does not cause sexual dysfunction or weight gain is bupropion (Wellbutrin), mirtazapine (Remeron), amoxapine (Asendin), and maprotiline (Ludiomil).
These medications are amongst the few antidepressants that do not have sexual side effects. They work by variably inhibiting serotonin and norepinephrine reuptake, and their mechanisms are still poorly understood.