Question

An indirect-acting cholinergic agent used in the Tensilon® test is

a. edrophonium.
b. methacholine.
c. neostigmine.
d. phospholine.

Answer 1

The indirect-acting cholinergic agent used in the Tensilon® test is edrophonium.

Step-by-step explanation:

An indirect-acting cholinergic agent used in the Tensilon® test is edrophonium. The Tensilon test is performed to diagnose myasthenia gravis, a neurological disorder that affects muscle weakness. Edrophonium is a short-acting cholinesterase inhibitor that temporarily improves muscle strength in people with myasthenia gravis.

Answer 2

An indirect-acting cholinergic agent used in the Tensilon® test is A. edrophonium.

Step-by-step explanation:

Edrophonium is a short-acting anticholinesterase drug that inhibits the breakdown of acetylcholine, leading to an increase in the concentration of acetylcholine at the neuromuscular junction.

During the Tensilon® test, edrophonium is administered to diagnose myasthenia gravis, a neuromuscular disorder characterized by muscle weakness. In individuals with myasthenia gravis, the neuromuscular junctions are affected, leading to decreased muscle contraction.

By inhibiting the breakdown of acetylcholine, edrophonium temporarily improves muscle strength in individuals with myasthenia gravis. If there is a significant improvement in muscle strength after the administration of edrophonium, it suggests that the individual has myasthenia gravis.

Therefore the correct answer is A. edrophonium.