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Megaloblastic anemia develops as a result of deficiencies of ________and _______.

A. thiamin; riboflavin
B. vitamin B-6; folate
C. folate; vitamin B-12
D. vitamin K; folate
E. All of these choices are accurate

1 Answer

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Final answer:

Megaloblastic anemia develops as a result of deficiencies of vitamin B12 and folate. Vitamin B12 is essential for the normal maturation and development of erythrocytes, DNA synthesis, and conversion of methyl malonyl-CoA to succinyl-CoA.

Step-by-step explanation:

Megaloblastic anemia develops as a result of deficiencies of vitamin B12 and folate. Lack of meat or a viable alternate source, and overcooking or eating insufficient amounts of vegetables may lead to a lack of folate.

Vitamin B12 is essential for the normal maturation and development of erythrocytes. It is necessary for the synthesis of DNA and required for the conversion of methyl malonyl-CoA to succinyl-CoA.

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