Final answer:
In an active shooter incident, the first activity according to the Illinois State Police Directives Manual is to secure one's own safety and escape if possible.
Step-by-step explanation:
In an active shooter incident, the activity that should be conducted first according to the Illinois State Police Directives Manual is to secure one's own safety and escape if possible.
It is important to prioritize personal safety and remove oneself from the immediate danger before attempting to intervene or assist others.
Once safety is ensured, individuals should then notify law enforcement and provide them with any information that can help in resolving the situation.