Final answer:
Patients with papulosquamous disorders like cutaneous aspergillosis require a diagnosis through patient history, respiratory fluid samples, serological tests, and histopathology. Treatment typically involves antifungal medications such as voriconazole, itraconazole, or amphotericin B, with potential surgery or immunotherapy for severe cases. Corticosteroids can mitigate allergic symptoms but must be used cautiously.
Step-by-step explanation:
To manage patients with papulosquamous disorders such as cutaneous aspergillosis, comprehensive diagnosis and treatment are crucial. Diagnosis is typically made by analyzing patient history, culturing respiratory fluid samples, and performing histopathology through a skin biopsy. Serological tests can identify Aspergillus antigens, and a skin test may determine past exposure to the fungus.
Treatment usually involves the use of antifungal medications. Voriconazole is preferred for invasive aspergillosis, but options include itraconazole and, if necessary due to ineffectiveness or intolerance, amphotericin B. In cases involving immunosuppressed individuals, including those with severe burns, adjunctive treatments such as surgery or immunotherapy may be necessary.
For allergic symptoms associated with aspergillosis, corticosteroids can be used to manage inflammation. However, corticosteroids should be discontinued in disseminated infections to enable a protective immune response.