Final answer:
Pemphigus foliaceus is characterized by skin erythema and fluid-filled blisters that heal slowly and may become infected. Patients also experience severe skin and mucosal pain and irritation, and in severe cases, it may cause respiratory distress.
Step-by-step explanation:
Clinical Manifestations of Pemphigus Foliaceus
The clinical manifestations of pemphigus foliaceus primarily involve the skin and present as skin erythema with fluid-filled blisters that heal slowly. These blisters can become infected, leading to further complications. It is common to see severe skin and mucosal pain and irritation alongside these symptoms. In severe cases, there can be respiratory distress and damage due to the spread of lesions. As an autoimmune condition, it can have varied symptoms, but the most striking are the clusters of blister-like lesions that crust over when they burst.