Final answer:
Corticosteroids, like hydrocortisone, have multiple mechanisms of action. One important mechanism is the downregulation of the immune system, which reduces inflammation. When applied topically, corticosteroids can relieve skin irritations, itching, and rashes by reducing histamine secretion.
Step-by-step explanation:
Corticosteroids, such as hydrocortisone, have multiple mechanisms of action in the body. One of their main mechanisms is the downregulation of the immune system, which helps to inhibit the inflammatory response. When corticosteroids, like hydrocortisone, are applied topically, they can reduce inflammation and temporarily relieve minor skin irritations, itching, and rashes by reducing the secretion of histamine, a compound produced by immune cells.