Final answer:
The administration of NTG should be adjusted if systolic blood pressure falls below 90 mm Hg to avoid hypotension, and it is important to keep diastolic blood pressure above 60 mm Hg to maintain adequate coronary perfusion.
Step-by-step explanation:
The endpoint for administration of nitroglycerin (NTG) when considering systolic blood pressure is typically recommended to be a systolic pressure less than 140 mm Hg. It is crucial to monitor blood pressure carefully because lowering blood pressure too much can lead to hypotension, which may cause harm to the patient. NTG is commonly used in the management of angina and other cardiovascular conditions where it is necessary to reduce the workload on the heart by dilating blood vessels and thus lowering blood pressure.
When treatment with NTG is initiated, the goal is to alleviate the symptoms for which the drug is prescribed while avoiding excessive hypotension. It is advised that systolic blood pressure should not drop below 90 mm Hg to prevent adverse effects. If a patient's systolic blood pressure falls below this threshold, the administration of NTG should be reassessed, and the dosage may need to be adjusted or discontinued. Additionally, for patients taking NTG, clinicians must ensure that the diastolic blood pressure does not drop below 60 mm Hg, as adequate coronary perfusion must be maintained.