Final answer:
For a 72 y/o female who has overdosed on propranolol, the administration of glucagon at an initial dose of 5-10 mg IV followed by an infusion can be an effective treatment. Continuous monitoring and adjunctive therapies may also be required.
Step-by-step explanation:
When a 72 y/o female has overdosed on propranolol, a medical command physician may consider using glucagon for its pharmacological counteractive effects against the beta-blocker toxicity. The usual initial dose recommended is 5-10 mg administered intravenously over 1 minute, which can be followed by an infusion of 1-5 mg per hour as needed for blood pressure and heart rate support.
It is important to monitor the patient's vital signs and blood glucose levels after administration. In cases where glucagon is ineffective or not available, higher doses of insulin combined with glucose may be considered. Additionally, supportive treatments such as intravenous fluids, atropine for bradycardia, and vasopressors may be necessary depending on the patient’s condition.