Final answer:
The legal significance of a nurse administering medication against a client's verbal refusal depends on the circumstances and jurisdiction. However, it could potentially involve informed consent and charges of battery.
Step-by-step explanation:
The legal significance of the nurse's action when a client verbally refuses his medication and the nurse gives it over his objection depends on the specific circumstances and legal jurisdiction. However, in general, this situation could potentially involve the principle of informed consent, where patients have the right to refuse treatment or medication. If the nurse administers the medication against the client's objection, it could be considered a violation of their autonomy and potentially lead to charges of battery, which is the intentional harmful or offensive touch without consent.