Final answer:
Patients intolerant to ACE inhibitors or ARBs can use Angiotensin-Receptor Neprilysin Inhibitors (ARNIs), or other medications like Candesartan, Irbesartan, and Valsartan, to treat heart failure symptoms and manage conditions such as high blood pressure and arrhythmias.
Step-by-step explanation:
Alternative Treatments for Heart Failure with Reserved Ejection Fraction
Patients with heart failure and a reserved ejection fraction who are intolerant to ACE inhibitors or ARBs may have alternative treatments available. Angiotensin-Receptor Neprilysin Inhibitors (ARNIs) are one such option, which combine a neprilysin inhibitor with an angiotensin receptor blocker to help relieve heart failure symptoms and slow down certain types of irregular heartbeat, such as atrial fibrillation. For those who cannot tolerate ACE inhibitors or ARBs, medications such as Candesartan (Atacand), Irbesartan (Avapro), and Valsartan (Diovan) may be used to manage their condition. Additionally, for emergency situations such as a hypertensive crisis, intravenous medications are employed to rapidly lower blood pressure and mitigate the risk of heart failure.