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Nicotine pharmacologic effects - low doses - pregnancy and lactation

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Nicotine, a highly addictive substance found in tobacco products, has stimulant effects that can lead to increased cardiovascular risks and is particularly harmful during pregnancy and lactation. Smoking cessation methods are available but must be evaluated for safety, especially vaping, which has been linked to serious health issues.

Step-by-step explanation:

Nicotine's Pharmacologic Effects During Pregnancy and Lactation

Nicotine is known to act as a stimulant by mimicking the action of the neurotransmitter acetylcholine and is highly addictive. It predominantly enters the body through the smoking or chewing of tobacco. Low doses of nicotine can have a significant impact on the autonomic system, increasing the risk of cardiovascular disease due to its effects on sympathetic and parasympathetic ganglia. Nicotine causes an increase in blood pressure and can also lead to arrhythmias. Pregnant women should be particularly cautious as nicotine is a teratogen, impacting fetal development and posing risks during lactation too.

In terms of smoking cessation, nicotine replacement therapies and various psychotherapeutic options have been explored to help individuals quit smoking. However, the use of vaping as an alternative has been found to carry significant health risks, including serious lung disease. Hence, understanding the pharmacologic effects of nicotine at low doses is essential, especially for pregnant and breastfeeding women, to minimize potential health risks to both the mother and child.

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User Obaydur Rahman
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