Final answer:
To administer the correct dose of granisetron, first convert 450 mcg to milligrams, which equals 0.45 mg. Then, divide this by the concentration of 0.1 mg per mL, resulting in an administered volume of 4.5 mL.
Step-by-step explanation:
The physician orders granisetron 450 mcg IV 30 minutes prior to chemotherapy. The label on the medication reads 0.1 mg per mL. To calculate how many mL the nurse will administer to the patient, we first need to convert the ordered dose from micrograms to milligrams, knowing that 1000 mcg is equivalent to 1 mg:
450 mcg = 450 / 1000 mg = 0.45 mg
Now that we have the ordered dose in the same unit as the label (mg), we calculate the volume of the medication to be administered using the label's concentration:
- 0.45 mg / (0.1 mg/mL) = 4.5 mL
Therefore, the nurse should administer 4.5 mL of granisetron to the patient.