Final answer:
Using a 23-gauge needle to collect a large evacuated tube may cause a loss of vacuum in the tube.
Step-by-step explanation:
Collecting a large evacuated tube using a 23-gauge needle may cause a loss of vacuum in the tube. When a vacuum is created in the tube, it allows blood to be drawn into the tube through capillary action. If the needle used to collect the blood is too large, it can cause a loss of vacuum and hinder the proper collection of the sample.