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What is high AFP + high bhCG

User Virna
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Final answer:

High AFP and high bhCG levels can indicate a potential relapse or presence of certain tumors, such as teratoma recurrence in children or tumors in adults. They are significant markers monitored post-treatment, and their trends can suggest the need for additional treatment or continued remission.

Step-by-step explanation:

High AFP (alpha-fetoprotein) and high bhCG (beta human chorionic gonadotropin) levels can have several medical implications. In the context of a child previously treated for teratoma, an elevated AFP may suggest a relapse with an endodermal sinus tumor, which indicates the need for further examination and possible treatment. Similarly, while high bhCG levels alone cannot confirm the presence of a tumor, they can be a significant indicator post-treatment. For example, after successful treatments such as surgery or chemotherapy, elevated BhCG levels should fall, and an increase might suggest a recurrence of the condition.

In women with polycystic ovary syndrome (PCOS), researchers have observed an association between high concentrations of anti-Mullerian hormone (AMH) and elevated LH levels. This led to further research on the effects of AMH on membrane potentials of GnRH expressing neurons.

User Im So Confused
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