Final answer:
Hepatocellular carcinoma is the most common primary malignancy of the liver.
Step-by-step explanation:
The most common primary malignancy of the liver is hepatocellular carcinoma, which accounts for 80% of all primary malignant liver tumors.
The primary malignancy of the liver is hepatocellular carcinoma (HCC). Hepatocellular carcinoma is the most common type of liver cancer and is characterized by the malignant transformation of hepatocytes, which are the main functional cells of the liver. HCC is responsible for a significant portion of global cancer-related deaths and is associated with various risk factors, primarily chronic liver diseases.