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Barrett's esophagus is replacement of lower esophageal squamous epithelium with columnar epithelium secondary to reflux. This is a ________malformation.

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Final answer:

Barrett's esophagus is an acquired metaplastic condition, where the lower esophageal squamous epithelium is replaced by columnar epithelium due to chronic acid reflux. It is not a malformation, as that term is generally used to describe congenital defects.

Step-by-step explanation:

Barrett's esophagus is the replacement of lower esophageal squamous epithelium with columnar epithelium secondary to gastroesophageal reflux disease (GERD). This condition is a result of chronic inflammation from acid reflux, leading to a metaplasia, where the normal tissue type transforms to another tissue type that is not typical for that location. Thus, Barrett's esophagus is an acquired metaplastic condition, not a malformation, because malformations are usually congenital defects that occur during development in utero.

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