Final answer:
The suffix 'megaly' in hepatosplenomegaly signifies the enlargement of an organ, specifically the liver (hepato-) and the spleen (spleno-) when combined in this term. It can be related to various diseases that cause abnormal enlargement of these organs.
Step-by-step explanation:
The suffix 'megaly' in the word hepatosplenomegaly refers to the enlargement of an organ or tissue. In the case of hepatosplenomegaly, it indicates the concurrent enlargement of both the liver (hepato-) and the spleen (spleno-). This condition can be associated with various diseases and abnormalities such as cirrhosis of the liver, multiple myeloma, lymphoma, leukemia, and infections caused by bacteria, viruses and protozoa.
Within the context of medical terminology 'megaly' is a suffix that commonly denotes the abnormal enlargement of organs. Diseases like hepatitis, which is inflammation of the liver, can lead to hepatomegaly or enlargement of the liver. Conditions such as thrombocytopenia can be a result of disorders involving organs like the spleen or liver which can lead to or be a consequence of hepatosplenomegaly.