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A client with hepatitis B (HBV) develops cirrhosis and is hospitalized. One potential sequela of chronic liver disease is fluid and electrolyte imbalance. The nurse determines that this may be attributed to a decrease in serum albumin level. Which of these conditions results from this imbalance?

1. Hemorrhage with subsequent anemia
2.Diminished resistance to bacterial insult
3.Malnutrition of cells, especially hepatic cells
4.Reduction of colloidal osmotic pressure in the blood

User Galen
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Final answer:

In chronic liver disease, low serum albumin levels lead to a reduction of colloidal osmotic pressure in the blood, which can cause fluid accumulation in tissues, edema, and ascites. This condition is the direct result of the decreased albumin synthesis by the damaged liver.

Step-by-step explanation:

Effects of Low Serum Albumin in Chronic Liver Disease

When a client with hepatitis B (HBV) develops cirrhosis, one of the complications that can arise is fluid and electrolyte imbalance due to a decrease in serum albumin level. This decrease in albumin concentration can occur in chronic liver disease due to the liver's impaired ability to synthesize proteins. Considering the options given, reduction of colloidal osmotic pressure in the blood occurs when serum albumin levels decrease because albumin is primarily responsible for maintaining the oncotic pressure necessary for the balance of fluid between blood vessels and surrounding tissues. Lower serum albumin levels lead to an imbalance, causing fluid to accumulate in tissues, resulting in edema and ascites. This condition is most directly related to the reduction of colloidal osmotic pressure in the blood.

Other conditions such as hemorrhage with subsequent anemia, diminished resistance to bacterial insult, and malnutrition of cells can also occur as a result of chronic liver dysfunction, but these are not primarily related to the reduction of serum albumin levels and the associated colloidal osmotic pressure changes.

User Binary Baba
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