Final answer:
Mastectomy is the gold standard treatment for diffuse and multicentric Ductal Carcinoma In Situ (DCIS), involving the removal of the entire breast to achieve complete eradication of cancerous cells and reduce the risk of recurrence.
Step-by-step explanation:
The gold standard of treatment for diffuse and multicentric Ductal Carcinoma In Situ (DCIS) is mastectomy. DCIS is a non-invasive form of breast cancer, and when it is diffuse or multicentric, meaning it spans across multiple quadrants of the breast or appears in more than one location, localized treatments like lumpectomy are not typically viable. Mastectomy, which involves the removal of the entire breast, offers the best chance for complete removal of the cancerous cells and reduces the risk of recurrence. In some cases, reconstruction surgery may follow the mastectomy. Additionally, patients should discuss with their healthcare team about the potential benefits of adjuvant therapy, such as hormonal therapy, to reduce the risk of new breast cancer.