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The following are purposes of what:

a-The rights and well-being of human subjects are protected.
b-The reported trial data are accurate, complete and verifiable from source documents.
c-The conduct of the trial is in compliance with the currently approved protocol/amendment(s), with GCP, and with applicable regulatory requirements.

User Arul Suju
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Final answer:

The purpose of the listed items is related to ethical considerations in clinical trials. These include participant protection, data accuracy, compliance with protocols and guidelines, and participation by informed consent, all of which are overseen by Institutional Review Boards (IRBs).

Step-by-step explanation:

Importance of Ethical Considerations in Clinical Trials

The purposes stated: protection of human subjects, accuracy of trial data, and ensuring trial conduct adheres to approved protocols, Good Clinical Practice (GCP), and regulatory requirements are crucial aspects of clinical trials. Clinical trials must be conducted ethically to safeguard participants and ensure the integrity of research. Institutional Review Boards (IRBs) review proposed research to ensure it aligns with ethical regulations and standards. These protocols stem from a need to address historical ethical breaches in human experiments and aim to uphold the principles of autonomy, beneficence, nonmaleficence, and justice within trials. Thus, ethical oversight in research involving human participants is indispensable for maintaining the trust and safety of subjects and the scientific community.

Key objectives of these ethical considerations include informed consent, minimization of risk, ensuring the participants' rights, and willingness of participants to engage knowingly in a study. It is also imperative that data collected is precisely reflective of the trial's findings to preserve the validity of the research findings. Such stringent guidelines are pivotal to the advancement of the field of medicine, as they facilitate the conduct of necessary research while safeguarding the subjects that volunteer for such studies.

User Kardi Teknomo
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