Final answer:
An investigator needs to complete and sign a new 1572 form when there are significant changes in their qualifications or the study they are involved in.
Step-by-step explanation:
An investigator needs to complete and sign a new 1572 form when there are significant changes in their qualifications or the study they are involved in. The 1572 form is a Statement of Investigator that is required by the FDA (Food and Drug Administration) for clinical trials.
Some situations that may necessitate completing a new 1572 form include changes in the investigator's address or contact information, changes in the study protocol that affect their role, or if their FDA Form 1572 has expired. It is important for investigators to keep their information up to date to ensure compliance with regulatory requirements.