Final answer:
The Tenth Amendment is often at the center of controversy due to concerns by the Anti-Federalists that federal power is limited, preserving state sovereignty and ensuring certain powers are reserved for state governments or the people.
Step-by-step explanation:
The Tenth Amendment has been at the center of controversy regarding the division of powers in the federal system primarily because it's cited as limiting the power of the national government. Specifically, Anti-Federalists were concerned about a concentration of power in the national government, and the Tenth Amendment states that federal power is limited. This inclusion in the Bill of Rights was to ensure a class of powers, known as reserved powers, exclusive to state governments. These are powers not enumerated to the national government, nor prohibited to the states, thus reserved to the states or the people. This has led to varying interpretations over time, particularly concerning states' rights and federalism.