Final answer:
TRALI (Transfusion-related acute lung injury) is the leading cause of transfusion-related death reported to the FDA. It is a serious complication of blood transfusion that can result in respiratory failure and death.
Step-by-step explanation:
The leading cause of transfusion-related death reported to the FDA is TRALI (Transfusion-related acute lung injury).
TRALI is a rare but serious complication of blood transfusion that occurs when antibodies in the transfused blood react with the patient's white blood cells, leading to inflammation and lung injury. Symptoms can include shortness of breath, fever, and low blood pressure. In severe cases, it can result in respiratory failure and death.
It is important for healthcare providers to carefully screen blood donors and match blood products to the patient's needs to minimize the risk of TRALI.