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Testing Pearl - RAAS inhibitor use with angioedema

1 Answer

6 votes

Final answer:

Hereditary angioedema is a genetic condition that leads to recurrent swelling episodes, which might not respond to steroids. Icatibant, a bradykinin-receptor antagonist, is a treatment option mentioned for managing hereditary angioedema.

Step-by-step explanation:

The student's question revolves around the use of RAAS inhibitors in patients with angioedema, particularly hereditary angioedema which is caused by a genetic disorder affecting the C1 inhibitor protein. This condition may lead to recurring episodes of swelling in various body parts, including the respiratory and gastrointestinal tracts, as well as facial and limb muscles. In the reference provided, Icatibant, a bradykinin-receptor antagonist, is mentioned as a treatment for hereditary angioedema. Traditional treatments like steroids may not be effective for hereditary angioedema due to its genetic nature, making targeted therapies such as Icatibant crucial for managing this condition.

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